Brexit Minister David Davis said the withdrawal process will take Britain to "the threshold of the most important negotiation for this country for a generation".
After 40 weeks of topsy-turvy politics since the referendum vote last June, Prime Minister Theresa May will pull the trigger by invoking Article 50 of the Lisbon Treaty.
Formal talks between Britain and the EU must then wait for member states to approve more detailed negotiating rules and give an official mandate to European Commission Brexit negotiator Michel Barnier, officials said.
The European Commission said it was ready to begin the negotiations.
Responding to Mr Juncker's comments, Mrs May's official spokesman said: "We have said many times we are at the start of negotiations and let's see how it unfolds". But May was not able to trigger the talks until last week, when the British Parliament approved a bill authorizing the start of Brexit negotiations.
But like any divorce, things may not go to plan.
He said that "everything is ready on this side", and that the EU's executive arm stands ready to play its role once the letter of notification is actually sent. Those things have become part of life in the United Kingdom since it joined what was then called the European Economic Community in 1973.
At the same time, May faces threats by Scottish nationalists to call a new independence referendum that could break up the United Kingdom.
"Scotland is at a hugely important crossroads and we can not be in a position where we drift for the next two years without as much as a clue as to the impact leaving the European Union will have".
The EU's next attempt to maximise its leverage will be through its guidelines for Brexit, which lay out the bloc's priorities for talks.
"Yet it is only a week since Nicola Sturgeon announced her plans for an unwanted divisive second referendum out of the blue with no prior notice to anyone".
May has said she wants to make Brexit as painless as possible.
Dr Hannah White, IFG's director of research, said: "The legislation required for Brexit will leave little parliamentary time for anything else - and making a success of it will require a large volume of bills and secondary legislation to be passed by Parliament against a hard deadline".
"However, in the quiet data period ahead, that seems like less of a risk than normal, in no small part because Brexit-related uncertainty is unlikely to decline significantly anytime soon". The first potentially contentious issue on the agenda will be the price Britain must pay to "buy itself out" of existing European Union commitments.
British negotiators are sure to quibble over the size of that tab.
The Prime Minister is attempting to reach out in order to address criticisms that she is not paying proper attention to different administrations.
Sapin says he hopes the negotiations between Britain and the European Union "can be done in a constructive manner, by both sides". Few, if any, have held out the prospect of a sweet deal for Britain. It is then likely to be some years thereafter before it has finalised a trade deal with the European Union, if indeed it is able to do so.
Not long after, SpaceX reported that EchoStar XXIII had been safely deposited in a geosynchronous transfer orbit. The company is also working on another upgrade of the Falcon 9 known as Block 5, which will be easier to reuse.
So long as there are tennis gods, they will let whatever Novak Djokovic and Nick Kyrgios have now fester into a proper blood feud. But he unraveled with 25 unforced errors, including a forehand service return on Kyrgios' second match point.
During the last Scottish independence referendum in 2014, 55 percent of voters opposed Scotland breaking away from the UK. British members of parliament on Monday rejected changes to the Brexit bill that had been backed by the House of Lords.
Since then, traders have complained of daily losses and prices of goods imported from Pakistan rose sharply in Afghanistan. He said recent incidents of terrorism in Pakistan have been traced back to anti-Pakistan elements in Afghanistan.
Both Pablo Carreno Busta , age 25, and Jack Sock , age 24, were at career-high rankings of 23 and 18 respectively. He pushed the Swiss number two, but Federer was too strong in the end, taking the match 6-2, 7-6 (4).
While EMTs know their vital work can be risky , they don't expect violence, Fire Commissioner Daniel Nigro said Friday. A man has been charged with stealing an ambulance and killing an FDNY EMT by running her over Thursday night.
James Roman Catholic Church in Lititz, explained Monday. "Fish on Friday, even this Friday, is certainly not a bad thing". No provision is made for a "conditional" or "do it if you insist" dispensation such as Bishop Braxton has promulgated.
As they showed against Sevilla , their nearly unique style of play means they can be a match for nearly anyone in Europe. That's how little Leicester, the reigning champions of England, reached the last eight in Europe.
Glenn Grothman of Wisconsin is concerned with how many employers would provide coverage under the Republican-sponsored plan. But Trump still appeared open to some improvements to the bill, speaking in support of the ultimate product.
For a fleeting, exquisite moment in December, we all thought Drake and J-Lo might be dating or at least collaborating. Love him or hate him, there's no denying that Drake is one of the hardest working guys in the game.
Purdy received his permit in May 2016 and is also the owner of three other venomous snakes and two venomous lizards, the FWC said. To make things even weirder, the snake was apparently being watched by the snake owner's apprentice at the time it freed itself.
Indiana's richest man got much wealthier over the past year, according to calculations released Monday by Forbes magazine . President Donald Trump comes in on the list at No. 544, with a net worth of $3.5 billion.
Debra Clayton while she lay defenseless on the ground". "Let me be very clear, however", said Ayala, who was elected last Fall. The court filing said the case is not suitable for prosecution. "I have seen the video of Markieth Loyd executing Lt.
In an interview with Good Morning America , Eichenwald said other Twitter users followed suit, sending him strobing GIFs. Eichenwald dropped the case because he said he had figured out, without the court's help, who had sent him the tweet.
He's converted the previous five into three finishes inside the top six but also slipped to T14 and T33 in two of those events. Playing in record 95-degree heat, Nordqvist broke the tournament 54-hole record of 19 under set by Ai Miyazato in 2013.
The defender pounced on a poor Erik Pieters clearance at a corner three minutes from time to reward Chelsea for their dominance. Antonio Conte's men are now 13 points clear at the top of the table with another hard fixture ticked off the calendar.
However, speculation on the back of this tweet suggests that some Trump supporters could attempt to launch a boycott of the chain. Others sad although they're not McDonalds fans, the tweet inspired them to stop in to the restaurant for the first time in years.
One of the biggest changes that subscribers can expect to see is the disappearance of the five-star rating system. The thumbs-up, thumbs-down model implies that a user is being asked for their opinion.
Pogba is unlikely to wilt in the face of scrutiny that will again be rife when United line-up against Rostov on Thursday. A winning team needs balance and while Griezmann will solve one issue for United , it'll raise another issue for them.
Robart said there would be no hearing before Wednesday and asked the Justice Department for a response to Ferguson's motion. The Justice Department argued that Hawaii can't claim it's harmed so it doesn't have standing to bring the case.
Russia's anti-doping agency, Rusada, is also working to have its credentials restored. "There remains significant work to do". A Russian doctor has been banned for life from any involvement in athletics.
After winning four games in four days to take home the Big Ten tournament title, rest is a focal point for the Wolverines. I would be very happy with a win over OSU in the first round and I'm looking forward to the Spartans pulling the upset .